The toilet characters all have grotesquely distorted faces and necks, which are unsettling by design. Conversely the "good guy" characters all have human bodies and either cameras, loudspeakers, or televisions for heads.
Episode 2: One of the Skibidi Toilets has stubble and green feminine hair. Seemingly a transphobic joke since this one sings a woman’s lyrics in the Skibidi song.