In Episode 3A, during a flashback in which Andrew is buying Ashley gifts, the shopkeeper has a dog with a collar that lets it talk à la Pixar's Up. It doesn't die.
Female characters are often the recipients of violence, but it’s never overly drawn out or particularly worse than what happens to some of the male characters.
Andrew's mother assumes he's having an incestuous relationship with his sister if he (player) picks her over his parents, with her reasoning being "what else would you get from her to do this?".
On top of ignoring their children as they starved in that apartment, never calling them, begging for them (their children) to stop calling them, and pretending they're dead to get money from life insurance.
In a vision of Ashley's future, a hitman stabs them while they sleep. This is also implied if you check the closet when they are gathering their things after fleeing from the hitman.
I refuse to believe that Julia cuts herself, since when she "says she does it" it is super ambiguous, in addition to everyone who mentions that about her, either wants to bother her or is directly making fun of her, at no time is it directly seen or mentioned by her or by someone who loves her.
Andrew and Ashley have a toxic, codependent relationship with incestuous overtones, the severity of which depends largely on the route. At mildest, there’s uncomfortably intimate moments and at worst, they straight up have sex.