Beatriz, an immigrant from a poor town in Mexico, has drawn on her innate kindness to build a career as a health practitioner. Doug Strutt is a cutthroat, self-satisfied billionaire. When these two opposites meet at a dinner party, their worlds collide, and neither will ever be the same.
One character mentions momentarily a worry about becoming fat (not in a joking way and not more than a mention) during a phone call, but that's about it.
The one character makes an offhand comment about having OCD in what seems like a joking manner. And a lot of "insane" "crazy" etc. in a derogatory and offhand manner.
Only mentioned, not shown. Also one character who is technically a parent (his grown up kids are only mentioned not shown) appears to die in a scene, it's not reality.
It's not specifically framed as alcohol abuse, but there is a lot of drinking and one character who talks about how she shouldn't drink like that and then continues to drink.
One character's kid had cancer and it's discussed extensively but she's fine now. And the main character works in a clinic focusing on alternative therapies for cancer patients so it's mentioned and a couple of the patients are shown momentarily in a couple of scenes.