No, however, there is a scene where one of the main characters tries to pressure his girlfriend into having sex (i.e. he tries to sexually assault her). She lays still and tells him upset to just go ahead then, (implying that if he wants to have sex he will have to rape her instead), and then he stops.
No, however, there is a 12 year old girl who gets in a car with a man and expresses romantic interest in him. He does not reciprocate her interest, but they drive around all night, and at one point he pretends to be interested in her to get her to leave him alone. At another point, cops are nearby and she says she will tell the cops that he r**** her if he doesn't let her drive around with him. All of this is played for comedy, but isn't funny.
Additionally, there is a scene where an adult teacher and a 17 or 18 year old student walk off together, and his hand is on her back, so it is implied they might have a sexual relationship, but it is not shown. (Not pedophilia, but inappropriate sexual relationship (i.e. possible sexual assault) between an adult and someone they have power over who might be a minor)
A girlfriend gets back together with her boyfriend after he tries to pressure her to have sex with him and nearly sexually assaults her (she implies that if he keeps pushing she'll just lie there and he'll be r**ing her, and so he stops). Additionally, he was trying to push her to be in an open relationship prior to that. The relationship is not characterized as being otherwise or previously abusive.
A child character and an adult character argue with each other, but it is mutual and they're still friends. I know some people don't like seeing any yelling directed at kids so I wanted to put this here.
Steve kisses Laurie and tries to have sex with her while she's repeatedly telling him no and to stop.
He stops once she lies still and tells him, upset, to go ahead then (she does so to communicate that if he continues, it will be rape. This is very clear in the scene).
"Toad" the boy with glasses vomits offscreen. It cuts straight to the scene without warning so skip (or mute) from 1h 29m 35 seconds to 1h 29 minutes 55 seconds and you will not hear any of it. Although some people have said they didn't find it too bad, it still made me very uncomfortable but as it's offscreen it's definitely mute/skippable.
SPOILER A car rolls off the road, no one dies in this crash or is even harmed. After the events of the movie, a car crash happens off-screen and kills a character.