Ryder the dog is totally fine throughout the whole movie. He looks like he might get hit by a truck at one point but makes it out just fine and is bathed and fed.
Not overtly, but an 8 year old is said to have started her period, which apparently bothers horses. This is later revealed to be a lie to allow the doctor to get an embryo out of her.
A woman at a birthday party wears a really ugly, flesh-colored clown mask and does a weird dance. It's only a few seconds but pretty jarring. There are clowns all over the fair, and clowns show up at the orphanage where the PI is investigating Delia's parents.