On Leon and Helena’s campaign a player may be pulled and held underwater by an enemy during a cutscene (not sure if it happens every time but It happened to me lol)
One campaign features a repeating enemy who relentlessly stalks the player characters. If you're familiar with the main enemy of Resident Evil 3, the mechanics are very similar.
A main character is shown very drunk and implied to have been abusing alcohol for several months. After the opening cutscene, there are no further references to his drinking.
There’s a mission in Chris’ chapter where you are persistently stalked by a giant invisible snake which continually appears, devours one of your comrades, before leaving again.
At times in the story people are infected with viruses using needle implements(auto-injectors, syringe launchers) and healing a downed partner can be done with a syringe.
This is mostly done without graphical injections, with most the focus laying on virally induced mutations.
To add to the below comment, the plane crashes regardless of whether or not you are successful at piloting it, it just determines whether the characters survive or you get a game over.