Throughout the end of chapter two, if the player pays attention while in the music studio they may see the character Sammy Laurence from the recording booth staring down at them. [SPOILERS] who will soon wait for them behind a corner (during the objective return to sammys office) and proceed to knock the character out and kidnap them.
No one's head is squashed, bu there are head injuries. For example, an opponent has you down on the ground is getting ready to hit you in the head with an axe (telling you he will do so), when an ally comes from behind and plants an axe in the top of the opponent's head. They are ink creatures, so there is no blood or gore, but you see him collapse, with the axe sticking out of his head.
Your player character, Henry, is captured and tied up or locked in cells at various points of the game. As well, at the end of Chapter Three, a character is kidnapped while helping you; and Chapter Four is spent trying to rescue the character.
No one vomits in this game. Brute Boris's body cannot handle what Physical Alice has done to him, and he periodically stops to catch his breath, and his poorly constructed new body spurts ink all over the arena.
I wouldn’t exactly call it anxiety but there’s nowhere else to categorize this. There are themes of derealization and dissociation at the end of the game. the end reveals some form of time loop that may also be troubling to some players.
If you would note above, I have noted it while talking about strobe effects. There is an elevator, though it isn't as small as a normal one. The Alice Angel room is a bit cramped (spoiler: especially when you're sharing it with a mutilated version of her!), and there's a hallway where the developers used it. (Spoiler: While you're walking through it, the hallway switches to a view with hands reaching through the walls towards you, and slows your character, Henry, down somewhat, similar to the effect from Chapter 2 while walking through ink.) The trailer suggests a similar situation for Chapter 5.