A non-drinking party member prods at party members who do drink for the indulgence tendencies and calls them alcoholics, but no actual alcohol abuse occurs there.
There are multiple chapters devoted to trying to catch and then prepare "dungeon rabbits", which look exactly like normal rabbits except they have knives in their paws.
Several familiars die over the course of the manga, though in most cases they are considered disposable and the source of grief comes from the damage the familiar's death does to the magic user's mind.
There is a spell used to force the party to tell the truth and puts them in a stupor, and other spells that alter people's perceptions, but no drugging occurs. It does come up as an option at one point but is shot down for being infeasible.
There are jokes in a side comic of an elven character being a pedophile for being in relationships with half-foots, who have shorter lifespans and reach adulthood earlier. It’s a large age gap despite both being adults, so heads up for that. but it’s never seen on screen or in main comic if I’m correct.
a head is squashed in chapter 19 and chapter 38, though it is partially censored by the author's conscious choice. the reader can only see roughly drawn pulps and puddles of black ink.
It is referenced in a character's backstory that their entire village was killed, children included, and there are children present before a dangerous situation happens, but nothing occurs on-screen.
Every single party member and several other majorly featured characters dies at some point, but due to the dungeon's nature, almost all are revived. Death is mostly a non-issue.
Shown in side comics, Fleki is shown to be a frequent drug user and doesn’t OD, but gets very close to her limit and then transfers consciousness to her familiar. Imagery is very similar though.
Drool and snot feature frequently, and sometimes emphatic characters are drawn with spit coming from their mouths, but I can't recall a specific act of spitting as insult
Incarceration by authorities is a threat to the party for most of the series, but does not come to pass. There are occasional times when the party or others are held hostage, but no institutional imprisonment happens.
For being a show that’s pretty heavily centered on food, there are almost no chewing/slurping/other eating noises. Characters occasionally make appreciative noises about the food (mmm, yum, things like that) but even those are fairly quiet and not drawn out or gross.
There's a heavy theme of exaggerated appreciation for monsters, but it is framed as being of their role in the ecosystem rather than lust. The manga contains no sexual content, human or monster.