The “eyes” (cameras) of the robot Dewy are taken out and given to Jeff in the beginning of the movie. Dewy later gets one replacement camera, while the other hole is covered by an X.
Not sure it’s explicitly explained as cancer but we’re led to believe that’s the cause of his illness. Trigger wise- there’s a lot of rough/labored coughing that involves blood that may be triggering for anyone who has experienced someone deteriorating from lung cancer.
No one is described as autistic but Jeff’s behaviors can be seen as an allegory for autism. Finch /does/ act poorly towards him when he does not understand his commands and he even calls him “Rain Man”.