In a story that follows some lives and their respective reincarnations over time, Valerio is a prince in the year one thousand and a doctor of the S.e.r.t. in the year two thousand. Altea on the other hand is a princess, who after a thousand years was reincarnated as a university student who volunteers as a mission and it also operates in the same S.e.r.t.. Their antagonist, in the past as in the present, is a man who was an alchemist and who today is the evil director of the same hospital where the S.e.r.t. is located. of Valerio and Altea. A rather anomalous director, given that he takes advantage of the cover offered by his position to traffic drugs in a big way. A fourth character is added to the three, Herrmugnen, who in the story embodies the mythological figure of the giant hero.