Infected and uninfected wolves can attack the player, infected being referred to as Runners (and are pretty much impossible to avoid killing)
A group of enemies in the game are said to have killed healthy dogs for sport, you can see their corpses littered, and your player puts down one in a rather sad scene.
You can hunt in Days Gone, and several times you are forced to kill animals. Infected wolves are impossible to avoid once they find you, as they're called 'Runners'. A cutscene shows a dog dying.
A character is seen in a flashback to have been kidnapped with her sister, and someone attempts sexual assault on them. The person is killed, and is an unimportant unnamed enemy.
A lesbian couple is spied on.
While not shown directly to be autistic, there is a character who exhibits autistic traits who is treated poorly in their introduction and later indoctrinated into a cult. Their autism seems to be "cured" at this point as they act very normal from that point forward.
The main method of attacking zombies is with guns. Enemy camps will also have human enemies who use guns against you. The topic of gun rights is also mentioned in the game.
A group of enemies in the game are said to have killed healthy dogs for sport, you can see their corpses littered, and your player puts down one in a rather sad scene.