One character has lost an eye and uses a glass replacement but the loss of it isn't described in any great detail it's just mentioned that it happened.
Several times the black characters in the book are accosted by cops who use racist language to describe them. Idge excuses this behavior by saying one cop cried when his black father figure died.
Brief mention of a cat possibly being overfed and dying but it's not completely clear if it was really because of that or on account of old age, natural causes etc.